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小鼠的免疫淋巴细胞与适当的骨髓瘤系细胞融合,可产生分泌对小鼠H-2或Ia抗原的抗体的杂交瘤细胞系。建立的11株克隆系中,9株产生抗H-2抗体,2株产生抗Ia抗体。此11株是用3个不同的骨髓瘤细胞系和不同的免疫接种技术进行了17次融合而建立的。作者总结了以下几点:(1)有效而良
Mice immunocompetent lymphocytes are fused with appropriate myeloma lines to produce hybridoma cell lines that secrete antibodies to mouse H-2 or Ia antigens. Of the 11 clones established, 9 produced anti-H-2 antibodies and 2 produced anti-Ia antibodies. The 11 strains were established by 17 fusions with three different myeloma cell lines and different immunization techniques. The author summarizes the following points: (1) effective and good