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目的 :了解乙型肝炎患者应用干扰素 (IFN)治疗后对垂体前叶分泌促激素的影响。方法 :采用放射性免疫竞争法测定血中生长激素 (GH)、泌乳素 (PRL)、促肾上腺皮质激素 (ACTH)、黄体生成素 (L H)、促卵泡激素 (FSH)和促甲状腺激素 (TSH)。结果 :应用 IFN后 ,乙型肝炎患者血清中 GH和 ACTH水平呈现显著性的升高 (P<0 .0 5 ) ;而 PRL、L H、FSH和 TSH则无明显改变。结论 :应用 IFN治疗乙型肝炎可以发现 ,机体内的免疫系统和内分泌系统之间是相互影响、相互作用的
Objective: To understand the effect of interferon (IFN) on the secretion of progestin in the anterior pituitary of hepatitis B patients. Methods: The levels of GH, PRL, ACTH, LH, FSH and TSH in blood were measured by radioimmunoassay. . Results: Serum levels of GH and ACTH were significantly increased in patients with hepatitis B (P <0.05), while no changes in PRL, LH, FSH and TSH were found. Conclusion: The application of IFN treatment of hepatitis B can be found in the body’s immune system and the endocrine system are interaction and interaction