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目的探讨急性心肌梗死(AMI)近期并发症与血清心肌肌钙蛋白I变化的关系。方法用固相免疫层析技术检测AMI患者发病第1、3、5和7天的血清心肌肌钙蛋白I水平。根据结果将106例AMI患者分为血清心肌肌钙蛋白I强阳性组、阳性组和弱阳性组,分析并比较三组患者住院期间的心力衰竭、心律失常、缺血性胸痛、心源性休克和心脏性死亡的发生情况。结果血清心肌肌钙蛋白I强阳性组和阳性组的心力衰竭、缺血性胸痛和心脏性死亡的发生率明显高于血清心肌肌钙蛋白I弱阳性组(P<0.01),但前两组之间的发生率差异无统计学意义(P>0.05),心律失常和心源性休克的发生率三组之间差异无统计学意义(P>0.05)。结论血清心肌肌钙蛋白I水平的变化情况可做为估计AMI近期并发症的发生和预后过程的重要参考依据。
Objective To investigate the relationship between the recent complications of acute myocardial infarction (AMI) and serum cardiac troponin I. Methods The levels of serum cardiac troponin I on the 1st, 3rd, 5th and 7th day of AMI were detected by solid phase immunochromatography. According to the results, 106 patients with acute myocardial infarction (AMI) were divided into two groups: strong positive cardiac troponin I group, positive positive group and weak positive group. Heart failure, arrhythmia, ischemic chest pain, cardiogenic shock And the incidence of cardiac death. Results The incidences of heart failure, ischemic chest pain and cardiac death were significantly higher in serum cardiac troponin I positive group and positive group than those in weak positive cardiac troponin I group (P <0.01) (P> 0.05). There was no significant difference between the three groups in the incidence of arrhythmia and cardiogenic shock (P> 0.05). Conclusion The changes of serum cardiac troponin I level can be used as an important reference for estimating the occurrence and prognosis of recent AMI complications.