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目的:分析宫颈CIN的临床病理学特征、诊断及治疗方法。方法:收集2010年1月-2012年1月期间,我院收治的CIN患者共160例,取患者的宫颈上皮内瘤进行分析,并在光镜下观察其特点并进行分级。结果:本组160例患者共检出83例(51.9%)CINⅠ级,61例(38.1%)CINⅡ级,16例(10.0%)CINⅢ级。术前术后的病例诊断符合率为81.9%,CINⅡ级的诊断不符合率最高;Ⅰ-Ⅲ级患者中,共有103例患者进行了宫颈环锥切,占64.4%;另57例患者进行了子宫全切,占35.6%。结论:对CIN患者进行宫颈三阶梯检查,可实现对宫颈CIN的早诊断及早治疗,对降低宫颈浸润癌发病率以及死亡率具有重要作用。
Objective: To analyze the clinical and pathological characteristics of cervical CIN, diagnosis and treatment. Methods: From January 2010 to January 2012, 160 cases of CIN in our hospital were collected. The patients with cervical intraepithelial neoplasia were analyzed and their characteristics were observed under light microscope and graded. Results: Totally 83 cases (51.9%) of CIN Ⅰ, 61 (38.1%) CIN Ⅱ and 16 (10.0%) CIN Ⅲ were detected in 160 patients. The coincidence rate of preoperative and postoperative diagnosis was 81.9%, and the diagnostic accuracy of CIN Ⅱ was the highest. Among Ⅰ-Ⅲ patients, 103 patients underwent cervical conization, accounting for 64.4%. Another 57 patients underwent Uterine total cutting, accounting for 35.6%. Conclusion: Three-step cervical examination of CIN patients can realize early diagnosis and early treatment of cervical CIN, and plays an important role in reducing the incidence of cervical cancer and mortality.