日本厚生省根据近年的报告,指出维生素K_2注射剂有严重的副作用,能使血压急剧下降。并且在此期间,出现严重副作用的患者达182人,其中14人死亡。因此,指示药品生产厂家须在该药品上注明“使用上注意”,并对医生发出“紧急安全性情报”以引起注意。维生素K与生成凝血因子有关,在因其缺乏引起血凝障碍而出血时,维生素K_2有止血作用。但有一女患者在手术两个月后,鼻出血不止,医院没有确认其 Japanese Ministry of Health under the report in recent years, pointed out that vitamin K_2 injection has serious side effects, can make a sharp drop in blood pressure. And during this time, there were 182 patients with serious side effects, 14 of whom died. Therefore, instruct the manufacturer of the drug to indicate “Use Caution” on the drug and issue “Emergency Safety Information” to the doctor for attention. Vitamin K and the formation of clotting factors, due to its lack of hemorrhagic disorders caused by bleeding, vitamin K_2 have a hemostatic effect. However, there is a female patient after surgery for two months, more than nosebleed, the hospital did not confirm it