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对109例急慢性肝病患者的血浆标本用放射免疫法进行了血亮脑啡肽(PLEK)的检测,另配对检测了80例肝病患者血清甘胆酸(SCG)。80例健康成人对照组进行上述两种检测。结果表明,各肝病组中的 PLEK 和 SCG 均明显增高(P<0.01)。此外,在肝硬化(LC)与原发性肝癌(PHC)组,PELK 以403.63pg/ml((?)±S)为界值,具有高度的敏感性(100%)和较好的特异性(70%),对上述两种疾病的鉴别诊断具有重要意义。
Blood samples of 109 patients with acute and chronic liver disease were detected by radioimmunoassay for leupeheniol enkephalin (PLEK), and the other matched pairs were detected in 80 patients with liver disease, serum glycocholic acid (SCG). Eighty healthy adult controls performed the above two tests. The results showed that PLEK and SCG were significantly increased in all liver disease groups (P <0.01). In addition, PELK was highly sensitive (100%) with better specificity (403.63 pg / ml (±) ± S) in patients with cirrhosis (LC) and primary liver cancer (PHC) (70%), the differential diagnosis of the two diseases is of great significance.