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目前口服补液已被公认为治疗腹泻性疾病的一种极重要的方法。1980年世界卫生组织正式推荐使用碳酸氢盐口服液(BBORS),其对纠正各种腹泻疾病的脱水具有良好的疗效,但也存在着化学性质不稳定,需要特殊包装及味觉不佳等缺点。为此,又研制了另一种性质稳定和味觉良好的柠檬酸盐口服液(CBORS)。为了比较这两种口服补盐液的疗效,作者在印度尼西亚的雅加达市进行了双盲对照试验。受试者为1983年11月～1984年4月在雅加达市传染病院每天门诊的前4名霍乱患者(年龄至少3岁,妊娠妇女除外),对门诊前12小时内至少腹泻3次,脱水程度≥5％者住院作粪便或直肠拭子病原菌培养。在治疗前30分钟,给药后8、24、48、72
Currently oral rehydration has been recognized as a very important method of treatment of diarrheal diseases. In 1980, the World Health Organization (WHO) officially recommended the use of bicarbonate oral liquid (BBORS), which has good curative effect on the dehydration of various diarrheal diseases, but also has the disadvantages of unstable chemical property, special packaging and poor taste. To this end, another development of a stable and good taste of citrate oral liquid (CBORS). To compare the efficacy of the two oral rehydration solutions, the authors conducted a double-blind controlled trial in Jakarta, Indonesia. The subjects were the top 4 cholera patients (aged at least 3 years of age, except pregnant women) who were daily outpatient in Jakarta City Infectious Diseases Hospital from November 1983 to April 1984, at least 3 diarrhea within 12 hours before clinic, and the degree of dehydration ≥ 5% were hospitalized for stool or rectal swab pathogen culture. 30 minutes before treatment, 8,24,48,72 after administration