链霉素硫酸盐(下称链霉素)是医疗上最常用的抗菌素之一。自临床上开始使用以来,常发生一些副作用,尤其在应用初期由于制品不纯,每毫克仅约350单位,且含有类组胺物质,可使外周血管舒张,动脉血压急剧下降,呕吐,对肾、肝亦有毒害,在注射局部出现红肿、剧痛……等。目前临床上所用的链霉素,虽然经过精制,但仍不是很纯的制品,国内外制品每毫克效价多仅在680～720单位之间,很少有超过740单位者(纯品每毫克应为798单位),尚约含有10%的杂质(不计水分),在临床应用时也还存在不良反应。由于制品本身不够纯,这些反 Streptomycin sulfate (hereinafter referred to as streptomycin) is one of the most commonly used medical antibiotics. Since the beginning of clinical use, there are often some side effects, especially in the early application of impure products, each milligram only about 350 units, and contains histamine substances, can make peripheral vasodilation, arterial blood pressure dropped sharply, vomiting, kidney , Liver also has poisoning, local injection in the inflamed, severe pain ... ... and so on. Currently used in clinical streptomycin, although refined, but still not very pure products, domestic and foreign products per milligram more than only between 680 to 720 units, rarely more than 740 units (pure per milligram Should be 798 units), still about 10% of the impurities (excluding moisture), there are still adverse reactions in clinical application. These products are not pure enough