过敏性紫癜（ HSP）是一种由免疫球蛋白A（ IgA）介导的全身性小血管炎，临床特征以非血小板减少性紫癜、关节炎或关节痛、腹痛及肾损害为主。儿童HSP是皮肤科常见疾病之一，大部分患儿病程呈自限性，但易复发。发病年龄晚、感染、食物过敏、剧烈运动、皮疹持续时间长或频繁反复、有消化道并发症、有肾损害、血小板计数增多、单核细胞数增多、血清IgG或IgA升高、D－二聚体升高、IgM－抗磷脂抗体阳性以及IgA－髓过氧化物酶型抗中性粒细胞胞质抗体阳性可能与儿童 HSP 复发有关，且频繁复发会对患儿的远期预后造成不良影响，临床医师应予以注意。“,”Henoch-Schonlein Purpura ( HSP) is an immunoglobin A ( IgA)-mediated systemic polyangi-tis,clinically characterized by non-thrombocytopenic purpura,arthritis or arthralgia,abdominal pain and renal damage.It′s a common disease in dermatology,which is self-limited,but relapse often occurs.The later onset age,infection,food allergy,strenuous exercise,persistent rash or repeated frequently rash,gastrointestinal tract complications,renal damage, increased platelet count, elevated serum levels of IgG or IgA, increased D-dimer,IgM antiphospholipid antibody positive and IgA perinuclear-pattern antineutrophil cytoplasmic anti-body positive may be related to the HSP recurrence.Frequent relapse can affect the long-term prognosis of children with HSP,calling for the due attention of the clinicians.