论文部分内容阅读
目的:了解宿迁市人群乙肝病毒(HBV)感染现状,评价乙肝疫苗纳入儿童免疫规划后的免疫效果。方法:采用整群随机抽样方法,抽取城市社区和行政村各1个,采集血标本710人份,用酶联免疫吸附实验(ELISA)法检测。结果:人群HBV感染率为17.04%,HBsAg阳性率为4.79%,均随年龄增加而增高,差异有统计学意义(HBV感染率χ2=24.30,P<0.01;HBsAg阳性率χ2=4.97,P<0.05)。抗-HBs阳性率为19.58%,单项抗-HBs阳性率为17.75%,阳性率均以5~14岁组为高。结论:实施新生儿乙肝疫苗免疫接种以来,宿迁市乙肝防制工作已取得明显成效。
Objective: To understand the current status of hepatitis B virus (HBV) infection in Suqian population and to evaluate the immune effect of hepatitis B vaccine in children’s immunization program. Methods: A cluster random sampling method was used to extract one city community and one administrative village, and 710 blood samples were collected and detected by enzyme-linked immunosorbent assay (ELISA). Results: The rate of HBV infection was 17.04% and the positive rate of HBsAg was 4.79% in the population, both of which increased with the increase of age (HBV infection rate χ2 = 24.30, P <0.01; HBsAg positive rate χ2 = 4.97, P < 0.05). The positive rate of anti-HBs was 19.58%. The positive rate of single anti-HBs was 17.75%. The positive rates of anti-HBs were all high in 5-14-year-old group. Conclusion: Since the immunization of newborns with hepatitis B vaccine, the prevention and control of hepatitis B in Suqian has achieved remarkable results.