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系统性红斑狼疮(SLE)是侵犯多脏器的自身免疫性疾病,近年来发病有增多趋势。国内报告的SLE中肺胸膜病变占73.1％,但目前认为致死原因以严重的心血管损害、肾脏病变、中枢神经系统损害及继发感染等为主。对肺胸膜病变一般认为由于激素的应用,预后较心、肾、中枢神经病变为佳。近年来我们遇到SLE2例,在多脏器病变中以弥漫性肺间质病变及膈肌病变为突出,对激素效果不佳,最后死于呼吸衰竭,2例都经尸检证实。 例1 女,14岁。1981年7月30日因发热1周住
Systemic lupus erythematosus (SLE) is a violation of multiple organs of autoimmune diseases, the incidence of an increasing trend in recent years. Domestic reports of pulmonary pleuropneumonia in SLE accounted for 73.1%, but currently considered the cause of death with severe cardiovascular damage, kidney disease, central nervous system damage and secondary infection, etc. based. Pulmonary pleurisy generally considered due to the application of hormones, the prognosis of heart, kidney, central neuropathy is better. In recent years, we have encountered SLE2 cases, with multiple interstitial lesions in diffuse interstitial lung disease and diaphragmatic lesions as prominent, poor effect on hormones, and finally died of respiratory failure, 2 cases were confirmed by autopsy. Example 1 Female, 14 years old. July 30, 1981 due to fever for 1 week to live