一些流行病学研究表明,高脂肪和低纤维素膳食是引起大肠癌的重要原因之一,并认为胆汁酸与大肠癌的发病机理有关。某些临床病例的对照研究发现,大肠癌患者粪便中含有高浓度的总胆汁酸和/或次级胆汁酸,但亦有报道未获得相似的结果。本研究旨在通过测定结肠癌和直肠癌患者 Some epidemiological studies have shown that high-fat and low-fiber diets are one of the important causes of colorectal cancer, and that bile acids are involved in the pathogenesis of colorectal cancer. A controlled study of some clinical cases found that patients with colorectal cancer had high concentrations of total bile acids and/or secondary bile acids in the feces, but similar results have not been reported. This study was designed to determine patients with colon and rectal cancer