支气管肺泡灌洗技术早在60年代初用于临床,主要是在治疗严重哮喘、支气管扩张和囊性纤维化时去除,患者呼吸道过多的分泌物和嵌塞的粘液。经纤维支气管镜对支气管肺泡灌洗并进一步分析研究是在70年代中期发展起来的。经国内外学者十多年的广泛深入研究证明:支气管肺泡灌洗液(BALF)的分析与肺组织活检有着良好的一致性,尤其对于阐明某些间质性肺部疾患的发病机理;结合临床进行疾病的辅助诊断;监测药物的治疗效果;判断疾病的预后转归都有一定的意义。近年来国外在间质性肺部疾患的BALF细胞 Bronchoalveolar lavage techniques were used clinically as early as the early 1960s and were mainly used in the treatment of severe asthma, bronchiectasis and cystic fibrosis, patients with excess respiratory secretions and implanted mucus. Bronchoscopic alveolar lavage with fiberoptic bronchoscopy was further developed in the mid-1970s. The domestic and foreign scholars for more than a decade of extensive research proved that: bronchoalveolar lavage fluid (BALF) analysis and lung biopsy has a good consistency, in particular, to clarify the pathogenesis of some interstitial lung disease; combined with clinical The diagnosis of the disease; monitoring the therapeutic effect of the drug; prognosis of the prognosis of the disease has a certain significance. In recent years, foreign BALB cells in interstitial lung disease