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目的：探讨院前早期应用奥美拉唑预防脑血管意外致应急性溃疡的效果。方法选取我中心治疗的112例脑血管意外患者，随机分为实验组和对照组，各56例，实验组在对照组常规治疗的基础上早期给予奥美拉唑对应激性溃疡加以预防，比较两组应激性溃疡的发生率。结果实验组SU的发生率低于对照组发，两组差异有统计学意义(<0.05)。结论在院前急救时如能第一时间使用奥美拉唑对SU加以预防，可以减少这种严重并发症的发生，为院内后续治疗打下良好基础。“,”Objective To study ef ect of omeprazole on prevention cerebrovascular accident stress ulcer in Pre-hospital. Methods 112 cases cerebrovascular accident patients in our center were randomly divided into experimental group and control group, 56 patients in each, the control were given conventional treatment, on the basis, experimental group were given stress ulcer omeprazole treated in early prevention, comparing the stress ulcer incidence of two groups. Results The incidence of SU is lower than the control group, the dif erences between the two groups have statistical significance ( <0.05). Conclusion Pre-hospital first aid and using omeprazole at first time, SU can be prevented, and reduce the serious complications, lay a good foundation for hospital subsequent treatment.