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目的探讨980 nm红激光治疗高龄高危浸润性膀胱癌患者的临床疗效。方法对2011年10月~2014年6月期间6例高龄高危不能耐受根治性全膀胱切除手术的浸润性膀胱癌患者,施行经尿道红激光膀胱肿瘤切除手术,现回顾性分析其临床资料。结果 6例患者术中生命体征均平稳,无闭孔神经反射及膀胱穿孔、尿外渗,手术顺利完成。术后留置尿管3~7 d,平均(3.0±0.6)d;术后住院5~8 d,平均(4.0±0.6)d。术后随访5~36个月,平均(16.0±0.8)月;其中2例复发者再次行红激光膀胱肿瘤切除手术。结论 980 nm红激光治疗高龄高危不能耐受根治性手术的浸润性膀胱癌患者是有效和安全的,具有手术时间短、术中出血少等优点,可以使患者生活质量获得最大限度的提高。
Objective To investigate the clinical efficacy of 980 nm red laser in elderly patients with high-risk invasive bladder cancer. Methods From October 2011 to June 2014, 6 patients with invasive bladder cancer who were not able to tolerate radical cystectomy in the elderly were enrolled in this study. The clinical data were retrospectively analyzed. Results All the 6 patients had stable vital signs during surgery, no obturator nerve reflex and bladder perforation and urine extravasation, and the operation was successfully completed. Postoperative catheterization 3 ~ 7 d, an average of (3.0 ± 0.6) d; postoperative hospital stay 5 ~ 8 d, an average of (4.0 ± 0.6) d. The patients were followed up for 5 to 36 months, with an average of (16.0 ± 0.8) months. Among them, 2 cases underwent resection of red laser bladder tumor. Conclusion The 980 nm red laser is effective and safe for patients with invasive bladder cancer who can not tolerate radical surgery in the elderly at high risk. It has the advantages of short operation time and less intraoperative bleeding, which can maximize the quality of life of the patients.