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肝门部胆管癌(HC)虽然发生率低,但预后较差,而外科手术仍是目前的唯一治愈手段.经历半个多世纪的发展,HC的外科治疗获得极大进展,随之而来的争议仍然存在.笔者就HC的术前分期及治疗、手术切除范围、血管切除与重建、淋巴结清扫数目及范围、腹腔镜手术、肝移植应用等方面的现状展开论述,为HC外科治疗提供借鉴.“,”Although the prevalence of hilar cholangiocarcinoma (HC) is relatively low,it is associated with dismal prognosis,and surgical resection remains the only curative treatment for this condition.Over more than half a century,considerable achievements have been made in surgical treatment of HC,meanwhile,the accompanied controversies still exist.The authors,in this paper,discuss the issues concerning the preoperative staging and management,and surgical resection scope,combined vascular resection with reconstruction,number and scope of lymph node dissection,laparoscopic procedure and liver transplantation for HC,so as to provide helpful guidance for surgical management of HC.