生酮饮食系一种高脂肪、低碳水化合物和适量蛋白质的特殊饮食，生酮饮食疗法是近年来治疗儿童难治性癫痫安全有效的重要措施，不但疗效确切，而且不良反应较少且多为一过性，一般预后良好。文章综述了生酮饮食治疗儿童难治性癫痫的有效率、依从性和不良反应及其产生原因。“,”The ketogenic diet (KD) is a special diet with high-fat, low-carbohydrate and moderate amount of protein. The KD therapy is a safe, potentially effective and important treatment of refractory childhood epilepsy in recent years. It has con-ifrmed clinical efifcacy and a generally good prognosis. The adverse reactions of KD treatment are normally less and transient. In this paper, the effective rate, patient compliance, adverse reactions and their causes of KD in treating children with refractory epilepsy were reviewed.