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近几十年来,国内外药学工作者应用近代科学技术,根据中药传统剂型的特点,研制出一些新的剂型。这些新的剂型也存在着一些问题。下面就中药新剂型中存在的一些问题进行探讨,并提出粗浅的看法。一、汤剂改为片剂工艺 1.提取方法上存在的问题中药新剂型的研制,在提取过程中都要本着尽可能的除去杂质,最大限度地保留有效成分,这样均需将原料药进行提取和精制。一般采取一系列的水提醇沉淀或醇提水沉淀,个别药物单煎,然后合并,部分药物粉碎等方法来处理,最后根据临床的需要加工成各种剂型。然而传统的汤剂在提取过程中采取的是分次煎煮,直
In recent decades, domestic and foreign pharmacists have applied modern science and technology to develop new dosage forms based on the characteristics of traditional Chinese medicine formulations. There are also some problems with these new dosage forms. The following is a discussion on some of the problems existing in the new dosage forms of traditional Chinese medicine, and puts forward superficial views. First, the decoction to the tablet process 1. Problems in the extraction method The development of new Chinese medicine formulations, in the extraction process should be based on the removal of impurities as much as possible, to maximize the retention of active ingredients, so that the need for raw materials Extraction and refining. Generally take a series of water-alcohol precipitation or alcohol precipitation precipitation, individual drugs, single fried, and then combined, some methods of drug smashing to deal with, and finally processed into various formulations according to clinical needs. However, the traditional decoction is taken in the process of extraction is divided into