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本文测定１６２例老年住院患者和３８例健康老人血清脂蛋白（ａ）［Ｌｐ（ａ）］水平。分析结果显示老年冠心病（ＣＨＤ）、脑梗塞（ＣＭ）患者Ｌｐ（ａ）浓度明显高于健康组和其他疾病组（Ｐ＜０．０１或Ｐ＜０．０５）。高Ｌｐ（ａ）血症的检出率ＣＨＤ组、ＣＭ组亦分别高于健康组及其他疾病组（Ｐ＜０．０１或Ｐ＜０．０５）。Ｌｐ（ａ）水平不受饮食和降脂药物等影响。认为脂蛋白（ａ）是缺血性心脑血管疾病的独立危险因素之一。提出Ｌｐ（ａ）可作为临床缺血性心脑血管疾病的重要预测指标。
This study determined the serum levels of lipoprotein (a) [Lp (a)] in 162 elderly inpatients and 38 healthy elderly. The results showed that the concentration of Lp (a) in elderly patients with coronary heart disease (CHD) and cerebral infarction (CM) was significantly higher than that in healthy subjects and other disease groups (P <0.01 or P <0.05). The detection rate of high Lp (a) hyperlipidemia was also higher in CHD group and CM group than in healthy group and other disease groups (P <0.01 or P <0.05). Lp (a) level is not affected by diet and lipid-lowering drugs. Lipoprotein (a) is considered as one of the independent risk factors of ischemic cardiovascular and cerebrovascular diseases. Proposed Lp (a) can be used as an important clinical predictors of ischemic cardiovascular disease.