通过对反应温度、混酸的比例、投料比及后处理中pH的控制的系统研究,探讨了影响反应收率的主要因素,发现了制备L-对硝基苯丙氨酸的最佳实验条件.放大实验证实了我们的研究结果.该合成方法简便,成本低,收率高(>83%),具有很高的工业应用价值. The main factors influencing the yield of the reaction were discussed through the systematic study on the control of the reaction temperature, the ratio of mixed acid, the feed ratio and the pH in the post-treatment. The optimum experimental conditions for the preparation of L-p-nitrophenylalanine were found out. The results of our experiment are confirmed by the enlargement experiment.The synthesis method is simple, low cost, high yield (> 83%) and has high industrial application value.