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目的 通过大量住院的非心脏病患者心电图资料的回顾、分析 ,初步了解特发性Brugada心电图征 (idiopathicBrugadaelectrocardiogrampattern)的发生率 ,获取有关中国人Brugada综合征流行病学的信息。方法 制定严格的筛选标准 ,调查了 2 30 82份近年住院的非心脏病患者的心电图资料 ,筛选出具有Brugada心电图征特征的心电图 ,并对部分患者进行随访跟踪。 结果 共获 31份具有Brugada心电图征特征的心电图 ,占总数的 1 34‰ ,其中男性 30例 ,女性 1例。初步随访了 6例患者 ,发现其中 3例的家系成员中有晕厥史或Brugada心电图征。结论 特发性Brugada心电图征在中国人中并非罕见 ,且男性远比女性多 ,其临床及遗传学意义有待进一步研究。
Objective To investigate the prevalence of idiopathic Brugada electrocardiogrampattern in a large number of inpatients with noncardiac electrocardiogram (ECG) data and to obtain information about the epidemiology of Brugada syndrome in Chinese population. Methods A rigorous screening criteria was established. The electrocardiogram data of 2 30 82 inpatients with noncardiac heart disease admitted in recent years were screened. The ECG with Brugada ECG signatures was screened and followed up for some patients. Results A total of 31 electrocardiogram (ECG) characteristics of Brugada were obtained, accounting for 1 34% of the total, including 30 males and 1 females. Initial follow-up of 6 patients, found that 3 of the family members have a history of syncope or Brugada ECG. Conclusions Idiopathic Brugada ECG is not uncommon in Chinese people, and there are more males than females. The clinical and genetic significance needs to be further studied.