目的探讨一种小鼠肿瘤相关膜蛋白在ＤＣＳ细胞表达的意义。方法用该蛋白抗体处理ＤＣＳ细胞，观察其对细胞生长速度、软琼脂克隆形成能力、粘附性、细胞运动能力、水解酶活性、侵袭性、体内转移率等生物学行为方面的影响。结果该抗体能抑制ＤＣＳ生长速度及克隆形成能力，增强琼脂糖悬滴细胞运动能力，余未见明显作用。结论该细胞膜蛋白可能调控小鼠肿瘤细胞增殖能力。 Objective To investigate the significance of a mouse tumor-associated membrane protein expression in DCS cells. Methods The DCS cells were treated with the protein antibody, and the biological behaviors such as cell growth rate, soft agar colony formation, adhesion, cell motility, hydrolase activity, invasiveness, and metastasis rate in vivo were observed. Results The antibody could inhibit the growth rate of DCS and the ability of colony formation and enhance the agarose suspension cell movement ability. No obvious effect was observed. Conclusion This cell membrane protein may regulate the proliferation of mouse tumor cells.