AIM To investigate the current management of gastric antral webs(GAWs) among adults and identify optimal endoscopic and/or surgical management for these patients.METHODS We reviewed our endoscopy database seeking to identify patients in whom a GAW was visualized among 24640 esophagogastroduodenoscopies(EGD) over a seven-year period(2006-2013) at a single tertiary care center. The diagnosis of GAW was suspected during EGD if aperture size of the antrum did not vary with peristalsis or if a “double bulb” sign was present on upper gastrointestinal series. Confirmation of the diagnosis was made by demonstrating a normal pylorus distal to the GAW.RESULTS We identified 34 patients who met our inclusion criteria(incidence 0.14%). Of these, five patients presented with gastric outlet obstruction(GOO), four of whom underwent repeated sequential balloon dilations and/or needle-knife incisions with steroid injection for alleviation of GOO. The other 29 patients were incidentally found to have a non-obstructing GAW. Age at diagnosis ranged from 30-87 years. Non-obstructing GAWs are mostly incidental findings. The most frequently observed symptom prompting endoscopic work-up was refractory gastroesophageal reflux(n = 24, 70.6%) followed by abdominal pain(n = 11, 33.4%), nausea and vomiting(n = 9, 26.5%), dysphagia(n = 6, 17.6%), unexplained weight loss,(n = 4, 11.8%), early satiety(n = 4, 11.8%), and melena of unclear etiology(n = 3, 8.82%). Four of five GOO patients were treated with balloon dilation(n = 4), four-quadrant needle-knife incision(n = 3), and triamcinolone injection(n = 2). Three of these patients required repeat intervention. One patient had a significant complication of perforation after needle-knife incision.CONCLUSION Endoscopic intervention for GAW using balloon dilation or needle-knife incision is generally safe and effective in relieving symptoms, however repeat treatment may be needed and a risk of perforation exists with thermal therapies. AIM To investigate the current management of gastric antral webs (GAWs) among adults and identify optimal endoscopic and / or surgical management for these patients. METHODS We reviewed our endoscopy database seeking to identify patients in whom a GAW was visualized among 24640 esophagogastroduodenoscopies (EGD) over a seven-year period (2006-2013) at a single tertiary care center. The diagnosis of GAW was suspected during EGD if aperture size of the antrum did not vary with peristalsis or if a “double bulb” sign was present on upper gastrointestinal series. Confirmation of the diagnosis was made by demonstrating a normal pylorus distal to the GAW. RESULTS We identified 34 patients who met our inclusion criteria (incidence 0.14%). Of these, five patients presented with gastric outlet obstruction (GOO), four of whom underwent repeated sequential balloon dilations and / or needle-knife incisions with steroid injection for alleviation of GOO. The other 29 patients were incidentally found to have a Non-obstructing GAW. The most frequently observed symptom prompting endoscopic work-up was refractory gastroesophageal reflux (n = 24, 70.6%) followed by abdominal pain (n = 11, 33.4%), nausea and vomiting (n = 9, 26.5%), dysphagia (n = 6, 17.6%), unexplained weight loss , 11.8%), and melena of unclear etiology (n = 3, 8.82%). Four of five GOO patients were treated with balloon dilation (n = 4), four- quadrant needle- knife incision (n = 3), and triamcinolone One patient had a significant complication of perforation after needle-knife incision. CONCLUSION Endoscopic intervention for GAW using balloon dilation or needle-knife incision is generally safe and effective in relieving symptoms however, repeat treatment may be needed and a risk of perforation exists with thermal therapies.