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目的观察氨溴索对新生儿肺炎氧合功能及肺通气、肺换气状态的影响情况。方法将2015年2月-2016年8月恩施州中心医院西医部儿科诊治的54例新生儿肺炎患儿随机分为对照组(27例)和观察组(27例),对照组患儿进行常规新生儿肺炎治疗,观察组患儿则在对照组常规治疗的基础上加用氨溴索,然后检测与比较两组新生儿治疗前后的氧合功能及肺通气、肺换气状态指标。结果治疗前对照组和观察组患儿的氧合功能及肺通气、肺换气状态指标比较,差异均无统计学意义(均P>0.05),而治疗后观察组患儿的氧合功能及肺通气、肺换气状态指标均明显好于对照组患儿,差异均有统计学意义(均P<0.05)。结论氨溴索可更为明显地改善肺炎新生儿的氧合功能及肺通气、肺换气状态,因此在新生儿肺炎中的应用价值较高。
Objective To observe the effects of ambroxol on neonatal pneumoconiosis and pulmonary ventilation and pulmonary ventilation. Methods From February 2015 to August 2016, 54 cases of neonatal pneumonia diagnosed and treated by the Department of Western Medicine of Enshi State Central Hospital were randomly divided into control group (27 cases) and observation group (27 cases). The control group received routine Neonatal pneumonia treatment, observation group of children in the control group based on the conventional treatment with ambroxol, and then test and compare the oxygenation function of both groups of neonates before and after treatment and pulmonary ventilation, pulmonary ventilation state indicators. Results Before the treatment, the oxygenation function and the index of lung ventilation and pulmonary ventilation in the control group and the observation group had no significant difference (all P> 0.05), while the oxygenation function in the observation group and the control group The indexes of pulmonary ventilation and pulmonary ventilation were significantly better than those of the control group (all P <0.05). Conclusions Ambroxol may improve the oxygenation function, pulmonary ventilation and pulmonary ventilation of neonates with pneumonia more obviously, so it has higher value in neonatal pneumonia.