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免疫复合物(IC)与自身免疫疾病的发病及病态形成有密切关系。作者曾报告,柴胡的果胶性多糖(bupleuran 2Ⅱb)具有使巨噬细胞的免疫球蛋白受体(FcR)增加,促进清除IC的活性,其内-α-(1→4)-聚半乳糖醛酸酶难溶性糖链结构部分(PG-1)为活性产生部位。此次对PG-1的结构进行了研究。
Immune complex (IC) is closely related to the pathogenesis and pathogenesis of autoimmune diseases. The authors have reported that the Bupleuran 2IIb of Bupleurum chinense has an increase in macrophage immunoglobulin receptor (FcR) and promotes the clearance of IC activity, and its inner-α-(1→4)-poly moiety The poorly soluble sugar chain structure portion (PG-1) of the lacturonase is the active site. The structure of PG-1 was studied this time.