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随着红细胞免疫功能(RCIF)在机体防御系统中潜在的巨大作用逐渐被发现和证实,近来已有人开始利用 RCIF 的检测指标进行药物的筛选研究。由于红细胞膜 C_3b 受体花环率(E-C_3bR)已被证实能较敏感地反映狼疮肾炎(LN)的病情发展及转归,我们利用该指标对多种中药针剂进行了筛选,发现其中的猪苓多糖在体外对 LN 患者 E-C_3bR 存在干扰作用,设计了本课题进行深入研究。
As the potential role of RCIF in the body’s defense system is gradually discovered and confirmed, people have begun to use the detection indicators of RCIF for drug screening research. Since the erythrocyte membrane C_3b receptor rosette rate (E-C_3bR) has been shown to more sensitively reflect the progression and outcome of lupus nephritis (LN), we have used this indicator to screen various Chinese medicine injections and found the pigs. Luteus polysaccharides interfere with E-C_3bR in patients with LN in vitro. The subject was designed for in-depth study.