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本文对1973—76年的30例儿童局限性尤文氏瘤在放疗的基础上加用四种化疗药物(长春新硷、环磷酰胺、阿霉素、甲基苄肼)的疗效进行了评价,并与原发灶位置相同,但未用大剂量化疗的30例作对照。两组病例诊断时均确诊为局限性病灶,两组照射量是,长骨病灶者整个骨照射6000rad/6周;椎骨病灶照射4500rad/4.5周;扁骨则包括较多的软组织在内照射4500rad。对残存灶补充1000～1500rad。强烈化疗组化疗方案见附表,在放疗的同时用化疗,当用甲基苄肼结束后休息3周,再用药,连续4～5个周期,并
In this article, 30 children with local Ewing’s tumors from 1973 to 76 years were evaluated on the basis of radiotherapy plus the efficacy of four chemotherapeutic agents (Cintraxime, cyclophosphamide, adriamycin, procarbazine). And compared with the location of the primary tumor, but not using high-dose chemotherapy in 30 cases as a control. Both groups were diagnosed with localized lesions at the time of diagnosis. The radiation dose in the two groups was that the long bone lesions irradiated the whole bone for 6000rad/6 weeks; the vertebral bone lesions were irradiated for 4500rad/4.5 weeks; the flat bone included more soft tissues and irradiated 4500rad. The residual lesions are supplemented with 1000-1500 rad. The chemotherapy regimen in the intensive chemotherapy group is shown in the attached table. At the same time as radiotherapy, chemotherapy is used. After the treatment with procarbazine, there is a rest for 3 weeks, and then the drug is administered for 4 to 5 consecutive cycles.