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目的观察普贝生促宫颈成熟和引产的临床效果及其安全性。方法将180例有引产指征,且无母婴禁忌证的产妇随机分成两组。实验组:将普贝生1枚放置于阴道后穹隆,若无不良反应,24h取出。对照组:2.5 IU缩宫素加入5%葡萄糖溶液500ml中摇匀,根据宫缩情况调节滴速。两组用药前后分别进行宫颈Bishop评分。结果用药后实验组宫颈评分提高有效率、阴道分娩率明显高于对照组,用药到临产平均时间少于对照组,而新生儿出生后评分两组无明显差异。结论普贝生是一种有效和安全的促宫颈成熟和引产药物,对母婴无明显不良影响。
Objective To observe the clinical effect and safety of Przewalski’s cervical ripening and induction of labor. Methods 180 cases of induction of labor induction and maternal and child contraindications of women were randomly divided into two groups. Experimental group: Pubei 1 placed in the vaginal vault, if no adverse reactions, 24h removed. Control group: 2.5 IU oxytocin added 5% glucose solution 500ml shake, adjust the drip rate according to the contractions. Cervical Bishop scores were applied before and after treatment in both groups. Results After treatment, the cervical score of the experimental group was improved, the vaginal delivery rate was significantly higher than that of the control group, the average time of medication to labor was less than that of the control group, but no significant difference was found between the two groups after birth. Conclusion Przewalski is an effective and safe method to promote cervical ripening and induction of labor, and has no obvious adverse effect on mother and infant.