1研究背景国内外有关肾素-血管紧张素(RAS)基因多态性与高血压及心血管疾病关系的研究仍没有实质性的突破,近年文献报道也有限。所见的几篇报道,都是样本数较少的横断面研究或是病例对照研究,缺乏影响较大、样本含量大的流行病学现况研究及病例对照研究, 1 Background The domestic and international research on the relationship between renin-angiotensin (RAS) gene polymorphism and hypertension and cardiovascular disease still has no substantial breakthrough, and there are limited reports in recent years. The few articles I saw were cross-sectional studies or case-control studies with a small sample size, lack of epidemiological status studies and case-control studies with large impact and large sample sizes,