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目的 探讨 SPECT脑血流断层显像对癫痫患者的临床意义。方法 检查前 1小时患者口服过氯酸钾 40 0 mg以封闭脉络丛 ,静脉注射显像剂 (99m Tc- ECD) 740～ 92 5 MBq后 2 0～ 30分钟进行脑断层显像。结果 SPECT、EEG、CT、MRI的异常率分别为 88.89%、 87.5 0 %、 15 .2 %和 2 7% ,经统计学处理 ,SPECT分别与 EEG、CT、MRI进行比较 ,P值分别为P >0 .0 5、 P <0 .0 0 1、 P <0 .0 0 1。结论 SPECT脑血流显像对癫痫病的诊断有较大的临床价值 ,灵敏度优于 CT和 MRI,与EEG较一致。
Objective To investigate the clinical significance of SPECT cerebral blood flow imaging in patients with epilepsy. Methods One hour prior to the procedure, patients were randomized to receive 40 0 mg potassium perchlorate orally, to block the choroid plexus, 99m Tc-ECD 740 2-92 5 MBq, and brain imaging for 20-30 minutes. Results The abnormal rates of SPECT, EEG, CT and MRI were 88.89%, 87.5%, 15.2% and 27% respectively. After statistical analysis, SPECT was compared with EEG, CT and MRI, P values were P > 0 .0 5, P <0 .0 0 1, P <0 .0 0 1. Conclusion SPECT cerebral blood flow imaging has great clinical value in the diagnosis of epilepsy. The sensitivity is better than that of CT and MRI, which is consistent with that of EEG.