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目的:应用Meta分析的方法估算新型冠状病毒肺炎（简称“新冠肺炎”）出院病例核酸检测再次阳性（简称“复阳”）的发生率，为出院病例的管理提供科学依据。方法:检索万方数据资源系统、中国期刊全文数据库（CNKI）、PubMed、Medline和Web of science等数据库，获取截至2020年8月31日新冠肺炎病例核酸复阳相关研究的文献。对文献进行筛选、评价和信息提取，应用STATA 16.0（试用版）软件计算合并的复阳发生率。结果:共纳入20篇文献，Meta分析结果显示，复阳的总发生率为13.5%（95%n CI：10.2%~16.8%）。按照标本类型进行亚组分析，采集咽拭子检测的复阳率为16.8%（95%n CI：13.8%~19.8%），鼻咽拭子检测的复阳率为17.1%（95%n CI：8.6%~25.6%）。随访14 d以内和14 d以上的复阳率分别为11.5%（95%n CI：8.1%~14.9%）和14.5%（95%n CI：8.3%~20.7%）。n 结论:应对新冠肺炎出院病例进行随访和核酸检测，以便及时发现复阳病例并采取管理措施，降低潜在的传播风险。“,”Objective:To estimate the rate of re-positive in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleic acid testing among discharged patients of coronavirus disease 2019 (COVID-19) using meta-analysis, so as to provide scientific evidences for management of discharged patients.Methods:A literature search was performed using the database platforms, including Wanfang Data Knowledge Service Platform, China Journal Full-text Database (CNKI), PubMed, Medline and Web of Science, to obtain research studies of COVID-19 published in Chinese or English till August 31, 2020. Data in each study were screened, evaluated and extracted information. Stata 16.0 (test version) software was used to calculate the incidence rate of re-positive.Results:A total of 20 reference articles were enrolled in the study. The results of meta-analysis showed that the overall incidence rate of re-positive in SARS-CoV-2 nucleic acid testing was 13.5% (95%n CI: 10.2%-16.8%). The analysis of subgroups by sample types showed the incidence rates of re-positive in using pharyngeal swab and nasopharyngeal swab samples were 16.8% (95%n CI: 13.8%-19.8%) and 17.1% (95%n CI: 8.6%-25.6%), respectively. The incidence rates of re-positive within 14 days of follow-up and over 14 days of follow-up were 11.5% (95%n CI: 8.1%-14.9%) and 14.5% (95%n CI: 8.3%-20.7%), respectively.n Conclusions:Discharged COVID-19 patients should be followed and tested for SARS-CoV-2 nucleic acid for early identification and management of recurrent positive cases, and reducing the potential risk of transmission.