论文部分内容阅读
bas和bcl-2是一对作用相反的凋亡促进和抑制基因，它们之间的平衡失控可能在肿瘤发生中起重要的作用。DNA倍体异常在人体多种肿瘤中被认为是重要的预后参数。我们应用流式细胞术和细胞免疫荧光技术对70例食管鳞癌和10例正常食管粘膜组织中凋亡基因bax和bcl－2蛋白和DNA倍体含量
Bas and bcl-2 are a pair of oppositely acting apoptosis-promoting and suppressing genes, and their unbalanced balance may play an important role in tumorigenesis. DNA ploidy abnormalities are considered to be important prognostic parameters in many types of human tumors. We used flow cytometry and cellular immunofluorescence techniques to detect apoptosis gene bax and bcl-2 protein and DNA ploidy in 70 cases of esophageal squamous cell carcinoma and 10 cases of normal esophageal mucosa.