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母亲携带的乙肝表面抗原(HBsAg)常可传染其婴儿,方式有二:一为出生期感染——宫缩开始至分娩结束(母-胎微输血和/或胎儿接触产道分泌物)发生的感染;一为出生后感染。本文是(在台北)用随机双盲安慰剂法观察105名母亲是HBsAg阳性的婴儿,出生后感染乙肝病毒(HBV)的情况。婴儿出生后立即注射乙肝免疫球蛋白(HBIG)1次(其中有些还在出生后3和6个月再注射1次),以预防出生期的感染。于3-4个月后用放射免疫法检测此被动抗体已阴转,并于出生后12个月时检测HBV标记物仍为阴性,而随后出现HBV感染(检测出
Hepatitis B surface antigens (HBsAg) carried by mothers can often infect their babies in two ways: one is infection at birth - an infection that occurs from the start of contractions to the end of childbirth (mother-to-child micro-transfusion and / or fetal exposure to the birth canal) ; One for post-natal infection. This article is a case study of 105 HBsAg-positive infants born to mothers infected with hepatitis B virus (HBV) in a randomized, double-blind, placebo-controlled trial in Taipei. Infants are injected with hepatitis B immunoglobulin (HBIG) immediately after they are born (some of them are injected once more 3 and 6 months after birth) to prevent infection at birth. The passive antibody was detected by radioimmunoassay 3-4 months later and was negative for HBV markers at 12 months after birth with subsequent HBV infection