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目的研究阴道细胞学检查对绝经后骨质疏松的性激素替代治疗(HRT)的指导作用。方法随机选取2007年1月～2008年1月在我院门诊因绝经后骨质疏松行激素替代治疗的妇女48人,以阴道细胞学检查结果指导激素用量,期限1年。监测其右前臂桡骨骨密度(BMD),血清碱性磷酸酶(AkP)及药物副反应发生情况。结果受检者骨密度上升,骨质吸收明显减少,有效率100%,药物副反应发生少。结论阴道细胞学检查在绝经后骨质疏松的激素替代治疗中有重要的指导作用。
Objective To investigate the guiding role of vaginal cytology in the treatment of postmenopausal osteoporosis with hormone replacement therapy (HRT). Methods Forty-eight women with hormone replacement therapy for postmenopausal osteoporosis were randomly selected from January 2007 to January 2008 in our hospital. The dosage of hormones was guided by the results of vaginal cytology for a period of one year. The right forearm radial bone mineral density (BMD), serum alkaline phosphatase (AkP) and drug side effects were monitored. Results Subjects increased bone mineral density, decreased bone absorption, the effective rate of 100%, fewer side effects of drugs. Conclusion Vaginal cytology plays an important role in the hormone replacement therapy of postmenopausal osteoporosis.