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肺癌术后5年生存率Ⅰ期约为55％,Ⅱ期约为30％,Ⅲ期约为20％。手术率Ⅰ期为75％,Ⅱ期为40％,Ⅲ期为40％,Ⅳ期为10％。尽管Ⅳ期病例均经严格筛选,5年生存率在10％以下者预后仍不良。但Ⅳ期非小细胞癌脑转移者行开胸术和开颅术可取得较好的治疗效果。本文就肺癌脑转移开颅术的适应症、术后生存期的延长、术后生存质量以及开颅术的危险性等问题进行讨论。目前,转移性脑肿瘤手术死亡率低,为0～5％。其中占肺癌脑转移85％的脑幕转移瘤手术较安全。脑转移死亡的直接原因往往不是恶性肿瘤,而是脑压迫和神经症状引起机体极度衰竭
The 5-year survival rate of lung cancer after surgery is about 55%, phase 2 is about 30%, and phase 3 is about 20%. The surgical rate was 75% for phase I, 40% for phase II, 40% for phase III, and 10% for phase IV. Although all cases of stage IV have been carefully screened, the 5-year survival rate below 10% is still poor. However, patients with stage IV non-small cell carcinoma brain metastases undergoing thoracotomy and craniotomy can achieve better results. This article discusses the indications of brain metastasis and craniotomy for lung cancer, prolongation of postoperative survival, postoperative quality of life, and the risk of craniotomy. At present, the mortality rate of metastatic brain tumors is low, ranging from 0 to 5%. Brain metastases, which accounts for 85% of lung cancer brain metastases, are safer. The direct cause of death from brain metastasis is often not a malignant tumor, but brain compression and neurological symptoms cause extreme body failure.