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USPXX和BP 1980年版收载的转篮法试验装置,差别是前者应用圆底烧瓶而后者为平底,其它大致相同。作者选用市售的6个片剂品种及含10mg去氢氢化可的松的NCDA Performance Standard Ⅱ,对于USP和BP装置对药物溶出速率的影响作了研究。结果表明,两种装置对市售片剂的溶出速率无显著影响,各药品在规定时间内的溶出速率均符合有关规定。但是NCDAPerformance Standard Ⅱ30分钟时的溶出
USPXX and BP 1980 version of the spin-basket test method contained in the difference, the difference is that the former application of round bottom flask and the latter for the flat, the other roughly the same. The authors selected commercially available 6 tablet varieties and NCDA Performance Standard II containing 10 mg Dehydrocortisone hydrocortisone to study the effect of the USP and BP devices on drug dissolution rates. The results showed that the two devices had no significant effect on the dissolution rate of the commercially available tablets, and the dissolution rates of the respective drugs within the prescribed time all met the relevant regulations. However, NCDAPerformance Standard II dissolves at 30 minutes