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目的探讨脑膜癌的临床、影像学及脑脊液特点。方法回顾性分析25例脑膜癌患者的临床、影像学及实验室检查资料。结果 25例患者中,男14例,女11例。头痛19例,恶心呕吐15例,复视7例,视力下降6例,听力下降5例,癫痫8例,智能减退6例,小便障碍6例。所有患者均行腰椎穿刺检查,脑脊液白细胞升高21例,蛋白升高17例,葡萄糖降低17例。25例患者均行MRI检查,脑膜强化征15例,脊膜强化征6例,脊髓内病变7例。结论脑膜癌是恶性肿瘤颅内转移的特殊形式,脑脊液细胞学检查是诊断金标准,影像学显示脑膜结节样或混合型强化是明确诊断的重要依据。
Objective To investigate the clinical, imaging and cerebrospinal fluid features of meningeal carcinoma. Methods Retrospective analysis of 25 cases of meningeal cancer clinical, imaging and laboratory tests. Results 25 cases of patients, 14 males and 11 females. Headache in 19 cases, nausea and vomiting in 15 cases, diplopia in 7 cases, vision loss in 6 cases, hearing loss in 5 cases, epilepsy in 8 cases, 6 cases of intellectual decline, 6 cases of urinary disorders. All patients underwent lumbar puncture examination, cerebrospinal fluid leukocyte increased in 21 cases, protein increased in 17 cases, 17 cases of glucose decreased. Twenty-five patients underwent MRI, including 15 cases of meningeal enhancement, 6 cases of meningeal enhancement and 7 cases of spinal cord lesions. Conclusion Meningioma is a special form of intracranial metastasis of malignant tumor. Cytological examination of cerebrospinal fluid is the gold standard of diagnosis. Radiographic imaging shows nodular or mixed enhancement of cerebrum as an important basis for the definite diagnosis.