在致炎因子刺激下,肝脏形成某些蛋白质的速率发生变化,有些急剧增加,如 CRP;有些明显降低,如白蛋白。这些蛋白质统称为急性期蛋白(acu-te-phase proteins,APP)。在这些 APP 中有一些是糖蛋白,由于聚糖链的结构变异,它们表现一些微小的不均一性。血浆中有些 APP 升高时常伴有糖化的改变。巨噬细胞产生的单核因子在调节 APP 基 Under the stimulation of proinflammatory cytokines, the rate of formation of certain proteins in the liver changes, some of which are drastically increased, such as CRP; some are markedly reduced, such as albumin. These proteins are collectively referred to as acu-te-phase proteins (APPs). Some of these APPs are glycoproteins that show slight inhomogeneities due to structural variations in glycan chains. Some of the elevated plasma APP often accompanied by saccharification changes. Monocytes produced by macrophages regulate APP