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短暂性脑缺血发作(transient ischemic attacks,TIA)是脑血管病中一个古老而又常见的问题。然而自提出TIA的概念到今天,在半个多世纪的时间里经过众多科学家的不懈研究,人们对TIA的认识从理论到临床实践都有了深刻的变化。TIA已经不仅仅是与脑血管病相关,其内涵和延伸涉及到了心血管病、周围血管病和代谢综合征等,并且与血管病相关的危险因素发生了千丝万缕的联系,从而覆盖了神经内科、心脏内科和血管外科等相关科室,一个“大血管病”的新理念逐渐浮出水面。本期主要探讨了TIA的诊断、病因及发病机制、TIA与其他血管病的关系,以及影像学、尤其磁共振弥散成像(Diffusion-weighted Imaging,DWI)在TIA研究中的应用等问题,希望能够引起同道们的关注和争论,使之对TIA的研究不断走向深入。
Transient ischemic attacks (TIA) are an ancient and common problem in cerebrovascular disease. However, since the concept of TIA was proposed to today, after more than half a century’s hard work by many scientists, people’s understanding of TIA has undergone profound changes from theory to clinical practice. TIA is not only related to cerebrovascular disease, its connotation and extension related to cardiovascular disease, peripheral vascular disease and metabolic syndrome, and vascular disease-related risk factors have been inextricably linked to cover Neurology, Cardiology and Vascular Surgery and other related departments, a new concept of “great vascular disease” gradually surfaced. This issue mainly discusses the diagnosis, etiology and pathogenesis of TIA, the relationship between TIA and other vascular diseases, and the application of imaging, especially the application of Diffusion-weighted imaging (DWI) in TIA, Aroused the concern and controversy of fellow citizens, and made the research of TIA go deeper and deeper.