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既往对充血性心力衰竭的药物治疗均以洋地黄和利尿剂为主,但在临床上常见到某些心力衰竭病例对这种治疗效果并不佳。近年来由于对洋地黄制剂的药物动力学及其临床应用的深入了解,以及β-肾上腺素能激动剂、血管扩张剂及强力利尿剂等的使用,对某些难治性小儿心力衰竭的治疗反应已有明显的改善。一般认为心力衰竭(以下简称心衰)是指心脏工作能力的障碍,心脏的泵功能减低,使心排血量不能满足全身组织代谢需要的状态。泵功能(心排血量)主要是根据以下几个主要因素进行控制和调节:(1)前负荷(以左
Past treatment of congestive heart failure with digitalis and diuretics are the main, but the clinical common to some cases of heart failure on the treatment effect is not good. In recent years, due to the deep understanding of the pharmacokinetics of digitalis preparations and their clinical application, as well as the use of β-adrenergic agonists, vasodilators and potent diuretics, the treatment of some refractory children with heart failure The reaction has been significantly improved. Generally believed that heart failure (hereinafter referred to as heart failure) refers to the obstacles to work ability of the heart, reduce the pump function of the heart, cardiac output can not meet the metabolic needs of the state of the whole body. Pump function (cardiac output) is mainly based on the following major factors for control and regulation: (1) before the load (left