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Kaufman 指出,应用抗代谢物5-碘-2′脱氧嘧啶核苷(5-iodo-2′deoxyuridine 简称 IUDR,IDUR 或IDU)能治疗人和兔的单纯疱疹性角膜炎。此药能阻止细胞增殖所必需的核苷酸、核糖核酸及脱氧核酸(简称 DNA)的合成。5-卤化脱氧核糖嘧啶对嘧啶代谢
Kaufman points out that herpes simplex keratitis in humans and rabbits can be treated with the antimetabolite 5-iodo-2’deoxyuridine (IUDR, IDUR or IDU). This drug can stop the proliferation of cells necessary for the synthesis of nucleotides, ribonucleic acid and deoxyribonucleic acid (DNA). 5-Halogenated deoxyribocyts for pyrimidine metabolism