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目的探讨步长稳心颗粒对原发性高血压患者心率变异性的影响作用。方法选择某院收入的原发性高血压患者86例,患者根据治疗方式不同分为两组,步长稳心颗粒组及对照组,对照组给予卡托普利治疗,步长稳心颗粒组在卡托普利治疗基础上添加步长稳心颗粒,对比两组治疗后血压变化及心率变异性相关指标变化。结果步长稳心颗粒组及对照组患者治疗后收缩压与舒张压均显著较治疗前降低,结果对比差异有统计学意义(P﹤0.05)。步长稳心颗粒组治疗后SDNN、SDANN、rMSSD显著高于治疗前及对照组治疗后(P﹤0.05)。两组患者治疗前后LF、HF、L/H对比显示,步长稳心颗粒组治疗后HF、L/H与治疗前及对照组治疗后对比差异有统计学意义(P﹤0.05)。结论原发性高血压患者应用步长稳心颗粒不但可显著降低血压,并能够显著改善患者心率变异性。
Objective To investigate the effect of Stephensing Wenxin Granule on heart rate variability in patients with essential hypertension. Methods Eighty-six patients with essential hypertension were included in this study. Patients were divided into two groups according to different treatment methods: Wenxin granule group and control group, control group received Captopril treatment, Based on Captopril treatment, step-stabilizing granules were added to compare the changes of blood pressure and heart rate variability after treatment. Results The results showed that the systolic blood pressure and diastolic blood pressure in Wenxin Granule group and control group were significantly lower than those before treatment, the difference was statistically significant (P <0.05). The scores of SDNN, SDANN and rMSSD in Wenxin Granule group after treatment were significantly higher than those before treatment and control group (P <0.05). The comparison of LF, HF and L / H before and after treatment in both groups showed that there was significant difference in the HF, L / H between the treatment group and the control group before and after treatment (P <0.05). Conclusion The patients with essential hypertension not only can significantly reduce the blood pressure, but also can significantly improve the heart rate variability.