论文部分内容阅读
三种唾液酸亚型５－乙酰神经氨酸（５ＡｃＮｅｕ）、５，９－二乙酰神经氨酸（５，９ＡｃＮｅｕ）和葡萄糖代神经氨酸（ＮｅｕＧｃ）皆从小鼠肿瘤腹水中通过阴离子交换树脂法获得．葡萄糖代神经氨酸（２μｇ／ｍｌ）体外显示抗钙调蛋白活性，另两种亚型在１０μｇ／ｍｌ浓度下仍不显示该生物活性．
The three sialic acid subtypes 5AcNeu, 5,9A diacetylneuraminic acid and NeuGc were removed from the tumor ascites of mice by anion exchange resin obtain. Glucose neuraminidase (2 μg / ml) showed anti-calmodulin activity in vitro and the other two subtypes did not show this bioactivity at a concentration of 10 μg / ml.