众所周知,抗结核药物作用于结核杆菌的同时,亦作用于肝脏,通过肝脏代谢,如异烟肼在肝内乙酰化,利福平在肝内代谢为脱乙酰基代谢产物。这就不可避免地引起肝脏的损害或对肝功产生影响,既要继续抗结核治疗,又要使损害的肝脏得已恢复,这两个问题处理恰到好处,绝非易事。这里,总结 As we all know, anti-TB drugs act on Mycobacterium tuberculosis at the same time, also act on the liver, through the liver metabolism, such as isoniazid in the liver acetylation, rifampicin metabolized in the liver as deacetylated metabolites. This will inevitably lead to liver damage or liver function, both to continue anti-TB treatment, but also to restore the damaged liver, these two issues just right, not easy. Here, to sum up