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木综厂队列1972年1月1日至1992年12月31日共收集恶性肿瘤病例和对照96对(OR=0.88),其中肺癌35对(OR=1.12),肝癌21对(OR=1.40),食道场15对(OR=0.00),胃场11对(OR=0.20),肠场8对(OR=0.33),其它癌6对,上述OR值均无显著性差异(P>0.05)。由于木综厂用锯末做燃料,全厂职工均有生活性接触木尘史,如果仅以职业接尘为暴露,就可能产生信息性偏倚中的非特异错分,使结果趋于无效。在木综厂合并某煤矿的队列中共收集恶性肿启和对照160对(OR=3.05),其中肺癌43对(OR=3.75)肝癌31对(OR=3.00),食道用24对(OR=4.00).胃场18对(OR=3.00).肠癌20对(OR=9.00),其它癌24对,全癌、肺癌、食道癌和肠癌的OR值有显著性差异(P<0.05或P<0.01),其余癌症的OR值无显著性。队列内的病例对照研究结果与回顾性队列研究的结果相似,由于队列内的病例对照研究具有省时省力节约经费等优点,该方法在职业癌的研究中具有一定价值,但应注意克服偏倚的影响。本调查认为木尘与肺癌、肠癌和食道癌的发病可能有一定关系。
From January 1, 1972 to December 31, 1992, a total of 96 pairs of malignant tumors and controls were collected (OR=0.88), 35 of them were lung cancer (OR=1.12), and 21 pairs of liver cancer were OR=1.40), 15 pairs of esophageal fields (OR=0.00), 11 pairs of gastric fields (OR=0.20), 8 pairs of enteral fields (OR=0.33), and 6 pairs of other cancers. There was no significant difference in values (P>0.05). As the wood integrated plant uses sawdust as a fuel, all employees in the plant have a history of living in contact with wood dust. If only professional exposure is exposed, non-specific misclassification in information bias may occur, and the results tend to be ineffective. A total of 160 pairs of malignancy and control were collected in the cohort of a coal mine integrated into a woodmill (OR=3.05), of which 43 pairs (OR=3.75) of liver cancers were OR-3.00, and the esophagus was used. 24 pairs (OR=4.00). Gastric field 18 pairs (OR=3.00). Twenty pairs of colorectal cancer (OR=9.00), 24 pairs of other cancers, significant differences in OR of total cancer, lung cancer, esophageal cancer, and colorectal cancer (P<0.05 or P<0.01). The OR value is not significant. The results of the case-control study in the cohort are similar to those of the retrospective cohort study. Because the case-control study within the cohort has the advantages of saving time and effort, the method has some value in the study of occupational cancer, but attention should be paid to overcoming bias. influences. This survey suggests that wood dust may have a relationship with the incidence of lung cancer, colorectal cancer, and esophageal cancer.