Isepamicin 是一种新型的氨基糖苷,由庆大霉素 B 衍生而得,已证明它对灭活酶的稳定性比其它氨基糖苷类强。而且不会被灭活庆大霉素的2-氨基糖苷-腺苷转移酶或氨基糖苷-乙酰转移酶所修饰,其肾毒性也比庆大霉素或丁胺卡那霉素低。有的作者已从不同的角度证实,Isepamicin 的抗菌活性和抗菌谱不论在体外还是在体内都与庆大霉素和丁胺卡那霉素相似,而且还证明对耐庆大霉素和丁胺卡那 Isepamicin, a novel aminoglycoside derived from gentamicin B, has been shown to be more stable against inactivated enzymes than other aminoglycosides. And will not be modified by 2-aminoglycoside-adenosyltransferase or aminoglycoside-acetyltransferase that inactivates gentamicin, and its nephrotoxicity is also lower than that of gentamicin or amikacin. Some authors have confirmed from different angles that the antibacterial activity and antibacterial spectrum of Isepamicin are similar to gentamicin and amikacin both in vitro and in vivo and have also demonstrated that gentamicin and butylamine Kana