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目的：比较吡哌酸滴丸与氯霉素滴耳液治疗化脓性中耳炎的疗效。方法：化脓性中耳炎３０例（男性１９例，女性１１例；年龄３２±ｓ１７ａ），用吡哌酸滴丸１～２丸放至鼓膜穿孔处，每日换药１次；同期用氯霉素滴耳液治疗２９例作对照，疗程均１４ｄ。结果：吡哌酸滴丸组和氯霉素滴耳液组总有效率分别为９３％和７０％（Ｐ＜０．０５），治愈天数分别为５．６±２．８ｄ和１２．０±２．８ｄ（Ｐ＜０．０１）。细菌清除率分别为６２％和２８％；细菌阴转率分别为８７％和４３％（Ｐ＜０．０１）。结论：吡哌酸滴丸是治疗化脓性中耳炎较满意的药物。
Objective: To compare the efficacy of pipemidic acid dropping pills and chloramphenicol ear drops in the treatment of suppurative otitis media. Methods: Thirty cases of suppurative otitis media (19 males and 11 females; age 32 ± s17a) were treated with piperacil drop pills 1 ~ 2 and placed on perforation of the tympanic membrane for 1 day. In the same period, Ear drops treatment of 29 cases as a control, treatment were 14d. Results: The total effective rates of pipemidic acid dropping pills group and chloramphenicol ear drops group were 93% and 70%, respectively (P <0.05), the healing days were 5.6 ± 2.8d and 12.0 ± 2.8d (P <0.01). The bacterial clearance rates were 62% and 28%, respectively; the bacterial negative conversion rates were 87% and 43%, respectively (P <0.01). Conclusion: Pipemidic acid drops pills are more satisfactory for the treatment of suppurative otitis media.