目的通过对2012年深圳市流感监测结果进行分析,探索流感流行规律,为制定流感防治措施提供依据。方法收集全市哨点医院的流感样病例数据,病原学检测结果和暴发疫情资料进行分析。结果 2012年深圳市的流感样病例占门诊急诊就诊总数百分比(ILI%)为4.15%,波动在3.16～5.56%之间。2012年全市哨点医院共采集ILI咽拭标本3 776份,分离出474株流感病毒,阳性率为12.6%,其中264株季节H3亚型(55.7%),150株B(Victoria,31.6%)亚型,55株B(Yamagata,11.6%)亚型,4株季节H1亚型(0.8%),1株甲型H1N1亚型(0.2%)。2012年全市报告了87起ILI暴发疫情,流感PCR检测阳性74起,其中乙型23起(26.7%),季节性甲型46起(53.5%),季节性甲型和乙型混合感染5起(5.8%)。结论 2012年深圳市流感活动较低,主要在上半年流行,3月初和6月初出现流行高峰。 Objective To analyze the influenza surveillance results in Shenzhen in 2012 to explore the prevalence of influenza and provide the basis for the development of influenza prevention and control measures. Methods The data of influenza-like cases in the sentinel hospitals in the city were collected, the results of pathogen tests and outbreaks were analyzed. Results In 2012, the number of flu-like cases in Shenzhen accounted for 4.15% of the total number of outpatient emergency visits, fluctuating between 3.16 and 5.56%. In 2012, 3 776 pharyngeal swab specimens were collected from sentinel hospitals in the city and 474 influenza viruses were isolated. The positive rate was 12.6%, of which 264 were H3 subtype (55.7%), 150 (B) (31.6%), 55 subtype B (Yamagata, 11.6%), 4 seasonal H1 subtype (0.8%) and 1 subtype H1N1 (0.2%). In 2012, 87 ILI outbreaks were reported in the city, of which 74 were positive for influenza PCR (23.7%), 46 (53.5%) seasonal A, and 5 (5%) seasonal A and B (5.8%). Conclusion In 2012, the influenza activity in Shenzhen was relatively low, mainly prevailing in the first half of the year and peaked in early March and early June.