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目的通过对2009年-2013年间宁波市江东区O型孕妇ABO抗体筛查情况分析,了解O型孕妇中ABO抗体异常人数和不同血型的抗体效价情况,为预防新生儿溶血病的发生提供依据。方法采用微柱凝胶抗人球蛋白试验检测12 488例O型孕妇ABO抗体。结果 >1:128 2254例,异常率18.05%。其中1:128占44.7%1:256占30.5%1:512占14.5%1:1024占7.6%1:2048占2.2%1:4096占0.5%。结论孕妇血清中ABO抗体效价的检测有利于早期诊断预防新生儿溶血病的发生。
OBJECTIVE: To investigate the ABO antibody screening status of O-type pregnant women in Jiangdong district of Ningbo during 2009-2013 to find out the number of ABO antibody abnormalities and antibody titer of different blood types in O-type pregnant women and to provide a basis for prevention of neonatal hemolytic disease . Methods The micro-column gel anti-human globulin test was used to detect ABA antibodies in 12 488 O-pregnant women. Results> 1: 128 2254 cases, the abnormal rate of 18.05%. Of which 1: 128 accounted for 44.7% 1: 256 accounted for 30.5% 1: 512 accounted for 14.5% 1: 1024 accounted for 7.6% 1: 2048 accounted for 2.2% 1: 4096 accounted for 0.5%. Conclusion Detection of ABO antibody titers in serum of pregnant women is helpful for the early diagnosis and prevention of hemolytic disease in newborns.