慢性阻塞性肺疾病(COPD)是一种常见病,严重影响人们的身体健康,已成为世界第四位主要死亡原因,其预后与肺动脉高压密切相关,早期干预,病变尚可逆转或延迟发展,发展到晚期,则病变处于不可逆阶段,治疗困难,预后极差[1]。因此,及时有效地纠正肺动脉高压、改善预后就成为COPD治疗中 Chronic obstructive pulmonary disease (COPD) is a common disease that seriously affects people’s health and has become the fourth leading cause of death in the world. Its prognosis is closely related to pulmonary hypertension. Early intervention can reverse or delay the development of COPD, Development to the late, the disease is in an irreversible stage, treatment difficulties, poor prognosis [1]. Therefore, timely and effective correction of pulmonary hypertension and improve prognosis have become COPD treatment